| Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
| Vitamin D3 | 📋 | ✍ | ⛔ | | 38585333 | Vitamin D level is inversely related to allergen sensitization for risking atopic dermatitis in early childhood |
| Curcumin | 📋 | ✍ | ⛔ | | 37233669 | Anti-Allergic Effect of Dietary Polyphenols Curcumin and Epigallocatechin Gallate via Anti-Degranulation in IgE/Antigen-Stimulated Mast Cell Model: A Lipidomics Perspective |
| Probiotics | 📋 | ✍ | ⛔ | | 38590477 | Probiotics in Allergy and Immunological Diseases: A Comprehensive Review |
| Ginsenosides | 📋 | ✍ | ⛔ | | 38150707 | Ginsenoside F2-Mediated Intestinal Microbiota and Its Metabolite Propionic Acid Positively Impact the Gut-Skin Axis in Atopic Dermatitis Mice |
| Micronutrients | 📋 | | ⛔ | | 38732239 | An Overview on Atopic Dermatitis, Oxidative Stress, and Psychological Stress: Possible Role of Nutraceuticals as an Additional Therapeutic Strategy |
| Ginseng | 📋 | ✍ | ⛔ | | 37569348 | Black Ginseng Extract Exerts Potentially Anti-Asthmatic Activity by Inhibiting the Protein Kinase Cθ-Mediated IL-4/STAT6 Signaling Pathway |
| Quercetin | 📋 | ✍ | ⛔ | | 37496407 | The Alleviating Impacts of Quercetin on Inflammation and Oxidant-antioxidant Imbalance in Rats with Allergic Asthma |
| Luteolin | 📋 | ✍ | ⛔ | | 38588651 | Luteolin Is More Potent than Cromolyn in Their Ability to Inhibit Mediator Release from Cultured Human Mast Cells |
| Resveratrol | 📋 | ✍ | ⛔ | | 38001807 | Resveratrol and Its Derivatives in Inflammatory Skin Disorders-Atopic Dermatitis and Psoriasis: A Review |
| Vitamin E | 📋 | ✍ | ⛔ | | 38186195 | Antioxidant defense of children and adolescents with atopic dermatitis: Association with disease severity |
| Apigenin | 📋 | ✍ | ⛔ | | 37128812 | Transcriptomics reveals apigenin alleviates airway inflammation and epithelial cell apoptosis in allergic asthma via MAPK pathway |
| Fucoidan | 📋 | ✍ | ⛔ | | 36293027 | Anti-Allergic Activity of Fucoidan Can Be Enhanced by Coexistence with Quercetin |
| Glycyrrhizic Acid | 📋 | ✍ | ⛔ | | 36099014 | Glycyrrhizic acid suppresses atopic dermatitis-like symptoms by regulating the immune balance |
| Nigella Sativa | 📋 | ✍ | ⛔ | | 36243604 | Effects of nigella sativa oil on allergic rhinitis: an experimental animal study |
| Melatonin | 📋 | ✍ | ⛔ | | 38387700 | Melatonin restores DNFB-induced dysbiosis of skin microbiota in a mouse model of atopic dermatitis |
| Berberine | 📋 | ✍ | ⛔ | | 35083737 | Berberine and its derivatives represent as the promising therapeutic agents for inflammatory disorders |
| Kaempferol | 📋 | ✍ | ⛔ | | 37393173 | Kaempferol therapy improved MC903 induced-atopic dermatitis in a mouse by suppressing TSLP, oxidative stress, and type 2 inflammation |
| Lactobacillus plantarum | 📋 | | ⛔ | | 38288067 | Probiotic Lactobacillus plantarum GUANKE effectively alleviates allergic rhinitis symptoms by modulating functions of various cytokines and chemokines |
| Wormwood | 📋 | ✍ | ⛔ | | 37604330 | In vitro and in vivo anti-eczema effect of Artemisia annua aqueous extract and its component profiling |
| Zinc | 📋 | ✍ | ⛔ | | 36265320 | Zinc supplement reduces allergic responses through modulating the p38 MAPK pathway activation in an allergic rhinitis mouse model |
| Bee Propolis | 📋 | ✍ | ⛔ | | 36235230 | Allergic Inflammation: Effect of Propolis and Its Flavonoids |
| Burdock | 📋 | | ⛔ | | 34757674 | Anti-IgE effect of small-molecule-compound arctigenin on food allergy in association with a distinct transcriptome profile |
| Prebiotics | 📋 | ✍ | ⛔ | | 38138183 | Probiotics and Prebiotics Orally Assumed as Disease Modifiers for Stable Mild Atopic Dermatitis: An Italian Real-Life, Multicenter, Retrospective, Observational Study |
| Sea Buckthorn | 📋 | ✍ | ⛔ | | 38397537 | Sea Buckthorn Flavonoid Extracted by High Hydrostatic Pressure Inhibited IgE-Stimulated Mast Cell Activation through the Mitogen-Activated Protein Kinase Signaling Pathway |
| Astaxanthin | 📋 | ✍ | ⛔ | | 38246005 | Role of cytokines and Th17/Tregs imbalance in the pathogenesis of otitis media with effusion. Modulation of Notch1/Hes1/mTORC1/S6k1 signalling pathway underlies the protective effect of astaxanthin |
| Blackcurrant | 📋 | ✍ | ⛔ | | 37109265 | A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study |
| Chlorogenic Acid | 📋 | ✍ | ⛔ | | 38301561 | Chlorogenic acid alleviates crayfish allergy by altering the structure of crayfish tropomyosin and upregulating TLR8 |
| Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 30892697 | The role of oral vitamins and supplements in the management of atopic dermatitis: a systematic review |
| Fisetin | 📋 | ✍ | ⛔ | | 37410860 | Fisetin alleviates chronic urticaria by inhibiting mast cell activation via MRGPRX2 |
| Licorice Root | 📋 | ✍ | ⛔ | | 36267759 | Inhibitory effects of isoliquiritin on an atopic dermatitis model through the CD177/JAK2/STAT pathway in vitro and in vivo |
| Mangiferin | 📋 | | ⛔ | | 38621336 | Inhibition of macrophage MAPK/NF-κB pathway and Th2 axis by mangiferin ameliorates MC903-induced atopic dermatitis |
| Medicinal Plants | 📋 | | | | 38603736 | Medicinal plants for allergic rhinitis: A systematic review and meta-analysis |
| Peony | 📋 | | ⛔ | | 36057224 | Paeonia lactiflora Pallas extract alleviates antibiotics and DNCB-induced atopic dermatitis symptoms by suppressing inflammation and changing the gut microbiota composition in mice |
| Arctigenin | 📋 | | | | 34757674 | Anti-IgE effect of small-molecule-compound arctigenin on food allergy in association with a distinct transcriptome profile |
| Astragalosides | 📋 | ✍ | ⛔ | | 36411656 | Research progress of astragaloside IV in the treatment of atopic diseases |
| Baicalein | 📋 | ✍ | ⛔ | | 33905439 | Extract of Scutellaria baicalensis induces semaphorin 3A production in human epidermal keratinocytes |
| Baicalin | 📋 | ✍ | ⛔ | | 34929516 | Baicalin ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice through modulating skin barrier function, gut microbiota and JAK/STAT pathway |
| Bromelain | 📋 | ✍ | ⛔ | | 37109265 | A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study |
| Chrysin | 📋 | ✍ | ⛔ | | 34100606 | Chrysin Inhibits Pseudo-allergic Reaction by Suppressing Mitochondrial STAT3 Activation via MAS-Related GPR Family Member X2 |
| Cinnamon | 📋 | ✍ | ⛔ | | 37187105 | Anti-inflammatory effect and metabolic mechanism of BS012, a mixture of Asarum sieboldii, Platycodon grandiflorum, and Cinnamomum cassia extracts, on atopic dermatitis in vivo and in vitro |
| Cordyceps | 📋 | ✍ | ⛔ | | 37030458 | Cordyceps militaris polysaccharide alleviates ovalbumin-induced allergic asthma through the Nrf2/HO-1 and NF-κB signaling pathways and regulates the gut microbiota |
| EGCG | 📋 | ✍ | ⛔ | | 37233669 | Anti-Allergic Effect of Dietary Polyphenols Curcumin and Epigallocatechin Gallate via Anti-Degranulation in IgE/Antigen-Stimulated Mast Cell Model: A Lipidomics Perspective |
| Fish Oil | 📋 | ✍ | ⛔ | | 38442638 | Comparison of treatment efficacy of omega-3 fish oil and montelukast in ovalbumin-protease-induced allergic rhinitis model in rats |
| Food | 📋 | | | | 37571232 | The Effect of Dietary Components of the Mediterranean Diet on Food Allergies: A Systematic Review |
| Formononetin | 📋 | | | | 36880662 | Natural isoflavone formononetin inhibits IgE-mediated mast cell activation and allergic inflammation by increasing IgE receptor degradation |
| Gardenia | 📋 | | ⛔ | | 36980282 | Topical Administration of Gardenia jasminoides Extract Regulates Th2 Immunity in OVA-Induced Mice |
| Lycopene | 📋 | ✍ | ⛔ | | 37607433 | Lycopene alleviates food allergy by modulating the PI3K/AKT pathway in peanut-sensitized BALB/c mice |
| N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 38376812 | N-Acetyl Cysteine Augments Adipose Tissue-Derived Stem Cell Efficacy on Inflammatory Markers and Regulatory T Cell System Balance in an Allergic Asthma Model |
| Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38442638 | Comparison of treatment efficacy of omega-3 fish oil and montelukast in ovalbumin-protease-induced allergic rhinitis model in rats |
| Rosmarinic Acid | 📋 | ✍ | | | 38417242 | Alleviation of allergic asthma by rosmarinic acid via gut-lung axis |
| Vitamin A | 📋 | ✍ | ⛔ | | 34920650 | Studying the Effects of Vitamin A on the Severity of Allergic Rhinitis and Asthma |
| Vitamin C | 📋 | ✍ | ⛔ | | 38415860 | Anti-allergic effect of vitamin C through inhibiting degranulation and regulating TH 1/TH 2 cell polarization |
| Angelica | 📋 | ✍ | ⛔ | | 38154523 | Sophora flavescens-Angelica sinensis in the treatment of eczema by inhibiting TLR4/MyD88/NF-κB pathway |
| Astragalus Root | 📋 | ✍ | ⛔ | | 33370169 | Astragalus Polysaccharides Attenuate Ovalbumin-Induced Allergic Rhinitis in Rats by Inhibiting NLRP3 Inflammasome Activation and NOD2-Mediated NF- κ B Activation |
| Black Pepper | 📋 | ✍ | ⛔ | | 33595153 | Piper nigrum extract attenuates food allergy by decreasing Th2 cell response and regulating the Th17/Treg balance |
| Cannabidiol | 📋 | ✍ | ⛔ | | 38059783 | Cannabidiol Inhibits IgE-Mediated Mast Cell Degranulation and Anaphylaxis in Mice |
| Chamomile | 📋 | ✍ | ⛔ | | 34658853 | The Mechanism Action of German Chamomile ( Matricaria recutita L.) in the Treatment of Eczema: Based on Dose-Effect Weight Coefficient Network Pharmacology |
| Elderberry | 📋 | ✍ | ⛔ | | 33881685 | The impact of Sambucus nigra L. extract on inflammation, oxidative stress and tissue remodeling in a rat model of lipopolysaccharide-induced subacute rhinosinusitis |
| Ellagic Acid | 📋 | ✍ | ⛔ | | 33525403 | Anti-Inflammatory Effects of Ellagic Acid on Keratinocytes via MAPK and STAT Pathways |
| Evening Primrose Oil | 📋 | ✍ | ⛔ | | 30065580 | Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study |
| Fig | 📋 | | ⛔ | | 36364740 | Efficacy and Safety of Fig ( Ficus carica L.) Leaf Tea in Adults with Mild Atopic Dermatitis: A Double-Blind, Randomized, Placebo-Controlled Preliminary Trial |
| Galangin | 📋 | | | | 38697189 | Ameliorative potential of galangin in murine model of ovalbumin-induced allergic rhinitis: a role of PI3K-PKB pathway |
| Gallic Acid | 📋 | | ⛔ | | 34815684 | Gallic Acid Ameliorates Atopic Dermatitis-Like Skin Inflammation Through Immune Regulation in a Mouse Model |
| Honey | 📋 | ✍ | ⛔ | | 35909403 | Anti-inflammatory properties of raw honey and its clinical applications in daily practice |
| Maitake Mushrooms | 📋 | | ⛔ | | 38053833 | Extracts of Grifola frondosa inhibit the MAPK signaling pathways involved in keratinocyte inflammation and ameliorate atopic dermatitis |
| Moringa Oleifera | 📋 | ✍ | ⛔ | | 31829185 | In vitro anti-allergic activity of Moringa oleifera Lam. extracts and their isolated compounds |
| Naringenin | 📋 | ✍ | ⛔ | | 37837514 | Naringenin ameliorates atopic dermatitis by inhibiting inflammation and enhancing immunity through the JAK2/STAT3 pathway |
| Persimmon | 📋 | | ⛔ | | 33401337 | Persimmon leaf extract protects mice from atopic dermatitis by inhibiting T cell activation via regulation of the JNK pathway |
| Pine Bark | 📋 | ✍ | ⛔ | | 29675725 | Effect of Pycnogenol® on an Experimental Rat Model of Allergic Conjunctivitis |
| Schisandra | 📋 | ✍ | ⛔ | | 37512164 | The Anti-Inflammatory and Skin Barrier Function Recovery Effects of Schisandra chinensis in Mice with Atopic Dermatitis |
| Skullcap | 📋 | ✍ | ⛔ | | 38543055 | Anti-Atopic Effect of Scutellaria baicalensis and Raphanus sativus on Atopic Dermatitis-like Lesions in Mice by Experimental Verification and Compound-Target Prediction |
| Spirulina | 📋 | ✍ | ⛔ | | 36789047 | Therapeutic efficacy of spirulina against ovalbumin and cigarette smoke-induced asthma-specific stress biomarkers in Sprague-Dawley rats |
| Sulforaphane | 📋 | ✍ | ⛔ | | 36319916 | Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms |
| Tangeretin | 📋 | | | | 31030096 | Tangeretin promotes regulatory T cell differentiation by inhibiting Notch1/Jagged1 signaling in allergic rhinitis |
| TUDCA | 📋 | ✍ | ⛔ | | 38450676 | Chemical chaperone TUDCA selectively inhibits production of allergen-specific IgE in a low-dose model of allergy |
| Vitamin B12 | 📋 | ✍ | ⛔ | | 35502578 | Efficacy and safety profile of antioxidants in the treatment of atopic dermatitis: A systematic review and meta-analysis of randomized controlled trials |
| Aloe Vera | 📋 | ✍ | ⛔ | | 33072415 | Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial |
| Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 37178572 | Alpha-linolenic acid improves nasal mucosa epithelial barrier function in allergic rhinitis by arresting CD4+ T cell differentiation via IL-4Rα-JAK2-STAT3 pathway |
| Balloon Flower | 📋 | ✍ | ⛔ | | 38433216 | Platycodon D protects human nasal epithelial cells from pyroptosis through the Nrf2/HO-1/ROS signaling cascade in chronic rhinosinusitis |
| Butyrate | 📋 | | ⛔ | | 38159175 | Sodium Butyrate Ameliorates Atopic Dermatitis-Induced Inflammation by Inhibiting HDAC3-Mediated STAT1 and NF-κB Pathway |
| Calycosin | 📋 | | | | 38331120 | Calycosin enhances treg differentiation for alleviating skin inflammation in atopic dermatitis |
| Conjugated Linoleic Acid | 📋 | ✍ | ⛔ | | 33206422 | Topical Application with Conjugated Linoleic Acid Ameliorates 2, 4-dinitrofluorobenzene-Induced Atopic Dermatitis-like Lesions in BALB/c Mice |
| CoQ10 | 📋 | ✍ | ⛔ | | 33743807 | The effect of Co-Q10 on allergic rhinitis and allergic asthma |
| Dihydromyricetin | 📋 | ✍ | ⛔ | | 34201934 | IgE-Induced Mast Cell Activation Is Suppressed by Dihydromyricetin through the Inhibition of NF-κB Signaling Pathway |
| Echinacea | 📋 | ✍ | ⛔ | | 33686410 | Echinacea purpurea water extracts suppress the release of chemical mediators from mast cells |
| Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 36777980 | Evaluating the Effect of Eicosapentaenoic Acid in Children With Atopic Dermatitis: A Randomized Triple-Blind Clinical Trial |
| Ginger | 📋 | ✍ | ⛔ | | 32312261 | Ginger Extract Versus Loratadine in the Treatment of Allergic Rhinitis: A Randomized Controlled Trial |
| Hesperidin | 📋 | ✍ | ⛔ | | 30488351 | The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model |
| Hyaluronic Acid | 📋 | ✍ | ⛔ | | 35679095 | Cell-Type Specific Expression of Hyaluronan Synthases HAS2 and HAS3 Promotes Goblet Cell Hyperplasia in Allergic Airway Inflammation |
| Iodine | 📋 | ✍ | ⛔ | | 38078671 | Nasal instillation of povidone-iodine ameliorates ongoing mucosal inflammation in a pre-sensitized murine model of Der p1-induced allergic rhinitis |
| Magnolol | 📋 | | | | 38541664 | Magnolol Reduces Atopic Dermatitis-like Symptoms in BALB/c Mice |
| Mint | 📋 | | ⛔ | | 37175425 | The Anti-Atopic Dermatitis Effects of Mentha arvensis Essential Oil Are Involved in the Inhibition of the NLRP3 Inflammasome in DNCB-Challenged Atopic Dermatitis BALB/c Mice |
| Myricetin | 📋 | | ⛔ | | 36649930 | Myricetin alleviated immunologic contact urticaria and mast cell degranulation via the PI3K/Akt/NF-κB pathway |
| Neferine | 📋 | | | | 37702907 | Neferine Attenuates HDM-Induced Allergic Inflammation by Inhibiting the Activation of Dendritic Cell |
| Peanut | 📋 | | ⛔ | | 31295634 | Peanut protein-polyphenol aggregate complexation suppresses allergic sensitization to peanut by reducing peanut-specific IgE in C3H/HeJ mice |
| Polyphenols | 📋 | | | | 38004216 | Dietary Polyphenols-Natural Bioactive Compounds with Potential for Preventing and Treating Some Allergic Conditions |
| Rosemary | 📋 | ✍ | ⛔ | | 37918369 | Inhalation of Spray-Dried Extract of Salvia rosmarinus Spenn Alleviates Lung Inflammatory, Oxidative, and Remodeling Changes in Asthmatic Rats |
| Selenium | 📋 | ✍ | ⛔ | | 35956310 | Advances in the Study of the Mechanism by Which Selenium and Selenoproteins Boost Immunity to Prevent Food Allergies |
| Silymarin | 📋 | ✍ | ⛔ | | 35614885 | Effect of herbal cream containing Fumaria officinalis and silymarin for treatment of eczema: A randomized double-blind controlled clinical trial |
| Tetrahydrocurcumin | 📋 | ✍ | | | 34116562 | Tetrahydrocurcumin alleviates allergic airway inflammation in asthmatic mice by modulating the gut microbiota |
| Wogonin | 📋 | ✍ | ⛔ | | 29977652 | Anti-inflammatory Effect of Wogonin on Allergic Responses in Ovalbumin-Induced Allergic Rhinitis in the Mouse |
| Andrographis | 📋 | ✍ | ⛔ | | 30684531 | Dehydroandrographolide inhibits IgE-mediated anaphylactic reactions via calcium signaling pathway |
| Anethole | 📋 | | | | 29062168 | Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3 + Regulatory T Cells and Inhibition of Th2 Cytokines in Mice |
| Anise | 📋 | ✍ | ⛔ | | 34493326 | The extract of black cumin, licorice, anise, and black tea alleviates OVA-induced allergic rhinitis in mouse via balancing activity of helper T cells in lung |
| Apple | 📋 | | ⛔ | | 33747463 | Boysenberry and apple juice concentrate reduced acute lung inflammation and increased M2 macrophage-associated cytokines in an acute mouse model of allergic airways disease |
| Apple Polyphenols | 📋 | | ⛔ | | 35739968 | Skin Care Product Rich in Antioxidants and Anti-Inflammatory Natural Compounds Reduces Itching and Inflammation in the Skin of Atopic Dermatitis Patients |
| Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 37267637 | Bergapten ameliorates combined allergic rhinitis and asthma syndrome after PM2.5 exposure by balancing Treg/Th17 expression and suppressing STAT3 and MAPK activation in a mouse model |
| Beta-Carotene | 📋 | ✍ | ⛔ | | 36354054 | Protective effect of β-carotene on OVA-induced food allergy in mice by strengthening intestinal epithelial barrier function and regulating intestinal microflora |
| Beta-Sitosterol | 📋 | ✍ | ⛔ | | 37066493 | β-Sitosterol protects against food allergic response in BALB/c mice by regulating the intestinal barrier function and reconstructing the gut microbiota structure |
| Boswellic Acid | 📋 | ✍ | ⛔ | | 36077254 | Evaluation of the Anti-Atopic Dermatitis Effects of α-Boswellic Acid on Tnf-α/Ifn-γ-Stimulated HaCat Cells and DNCB-Induced BALB/c Mice |
| Camphor | 📋 | ✍ | ⛔ | | 31341557 | Cinnamomum camphora Leaves Alleviate Allergic Skin Inflammatory Responses In Vitro and In Vivo |
| Catalpol | 📋 | | | | 38041954 | Inhibitory effects of catalpol on DNCB-induced atopic dermatitis and IgE-mediated mast cells reaction |
| Chlorella | 📋 | ✍ | ⛔ | | 26404252 | Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice |
| Chokeberry | 📋 | ✍ | ⛔ | | 37569351 | Wheatgrass-and-Aronia-Mixed Extract Suppresses Immunoglobulin E-Mediated Allergic Reactions In Vitro and In Vivo |
| Cinnamaldehyde | 📋 | | | | 37275806 | Anti-Inflammatory Effect of Cinnamaldehyde in a Mouse Model of 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis |
| Coconut Oil | 📋 | | ⛔ | | 28660089 | Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma? |
| Cranberry | 📋 | ✍ | ⛔ | | 31295634 | Peanut protein-polyphenol aggregate complexation suppresses allergic sensitization to peanut by reducing peanut-specific IgE in C3H/HeJ mice |
| Crocin | 📋 | ✍ | ⛔ | | 30400140 | Crocin Ameliorates Atopic Dermatitis Symptoms by Down Regulation of Th2 Response via Blocking of NF-κB/STAT6 Signaling Pathways in Mice |
| Cumin | 📋 | | ⛔ | | 37430973 | Aqueous Extract from Cuminum cyminum L. Seed Alleviates Ovalbumin-Induced Allergic Rhinitis in Mouse via Balancing of Helper T Cells |
| D-Mannose | 📋 | ✍ | ⛔ | | 36327873 | D-Mannose ameliorates DNCB-induced atopic dermatitis in mice and TNF-α-induced inflammation in human keratinocytes via mTOR/NF-κB pathway |
| Diosmetin | 📋 | | | | 33045572 | Anti-inflammatory effects of natural flavonoid diosmetin in IL-4 and LPS-induced macrophage activation and atopic dermatitis model |
| Diosmin | 📋 | ✍ | ⛔ | | 33302042 | Diosmin restores the skin barrier by targeting the aryl hydrocarbon receptor in atopic dermatitis |
| Eclipta Alba | 📋 | ✍ | | | 37487966 | A methanolic extract of Eclipta prostrata (L.) L. decreases inflammation in a murine model of chronic allergic asthma via inhibition of the NF-kappa-B pathway |
| Essential Fatty Acids | 📋 | ✍ | | | 18477332 | Efficacy of an essential fatty acid-enriched diet in managing canine atopic dermatitis: a randomized, single-blinded, cross-over study |
| Eugenol | 📋 | | | | 36756486 | IN VITRO AND IN SILICO ANTIBACTERIAL ACTIVITIES OF SYZGIUM AROMATICUM ESSENTIAL OIL AGAINST BACTERIA ASSOCIATED WITH OTITIS MEDIA IN CHILDREN |
| Fucoxanthin | 📋 | ✍ | ⛔ | | 35947424 | Fucoxanthin Prevents the Ovalbumin-Induced Food Allergic Response by Enhancing the Intestinal Epithelial Barrier and Regulating the Intestinal Flora |
| Gamma-Linolenic Acid | 📋 | ✍ | ⛔ | | 15500483 | Alterations of mast cell mediator production and release by gamma-linolenic and docosahexaenoic acid |
| Ginger extract | 📋 | ✍ | ⛔ | | 26403321 | Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation |
| Gingerol | 📋 | ✍ | | | 34934427 | Ginger-derived compounds exert in vivo and in vitro anti-asthmatic effects by inhibiting the T-helper 2 cell-mediated allergic response |
| Glabridin | 📋 | | | | 37584465 | Immunomodulatory effect of glabridin in ovalbumin induced allergic asthma and its comparison with methylprednisolone in a preclinical rodent model |
| Gotu Kola | 📋 | ✍ | ⛔ | | 32033291 | Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice |
| Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 35739968 | Skin Care Product Rich in Antioxidants and Anti-Inflammatory Natural Compounds Reduces Itching and Inflammation in the Skin of Atopic Dermatitis Patients |
| Hesperetin | 📋 | | | | 36494586 | Bioactivity-boosting strategy based on combination of anti-allergic O-methylated catechin with a Citrus flavanone, hesperetin |
| Honeysuckle | 📋 | | ⛔ | | 36889421 | A homogeneous Lonicera japonica polysaccharide alleviates atopic dermatitis by promoting Nrf2 activation and NLRP3 inflammasome degradation via p62 |
| L-Theanine | 📋 | ✍ | ⛔ | | 36727615 | Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation |
| Licochalcones | 📋 | | | | 36263976 | Licochalcone A inhibits IgE-mediated allergic reaction through PLC/ERK/STAT3 pathway |
| Magnesium | 📋 | ✍ | ⛔ | | 16406247 | Dietary intake of seaweed and minerals and prevalence of allergic rhinitis in Japanese pregnant females: baseline data from the Osaka Maternal and Child Health Study |
| Milk | 📋 | | ⛔ | | 34978666 | Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis |
| NMN | 📋 | ✍ | ⛔ | | 38064810 | Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma |
| Nobiletin | 📋 | ✍ | | | 27021766 | Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells |
| Oleuropein | 📋 | | | | 36314290 | Oleuropein Prevents OVA-Induced Food Allergy in Mice by Enhancing the Intestinal Epithelial Barrier and Remodeling the Intestinal Flora |
| Olive Oil | 📋 | ✍ | ⛔ | | 35780313 | Dietary olive oil enhances the oral tolerance of the food allergen ovalbumin in mice by regulating intestinal microecological homeostasis |
| Ollive Leaf extract | 📋 | ✍ | ⛔ | | 33571899 | A combination of Olea europaea leaf extract and Spirodela polyrhiza extract alleviates atopic dermatitis by modulating immune balance and skin barrier function in a 1-chloro-2,4-dinitrobenzene-induced murine model |
| Onion | 📋 | ✍ | ⛔ | | 38584568 | Treatment with onion bulb extract both prevents and reverses allergic inflammation in a murine model of asthma |
| Paeoniflorin | 📋 | | | | 35222003 | Circadian Pharmacological Effects of Paeoniflorin on Mice With Urticaria-like Lesions |
| Pectin | 📋 | ✍ | ⛔ | | 38417857 | Oral Administration of Apple Pectin Solution Improves Atopic Dermatitis in a Mouse Model |
| Peppermint Essential Oil | 📋 | ✍ | ⛔ | | 36578435 | Protective effects of inhalation of essential oils from Mentha piperita leaf on tight junctions and inflammation in allergic rhinitis |
| Perilla | 📋 | ✍ | | | 36322828 | Antiasthmatic Compounds Targeting β2-Adrenergic Receptor from Perilla frutescens Improved Lung Inflammation by Inhibiting the NF-κB Signaling Pathway |
| Pomegranate | 📋 | | ⛔ | | 36330147 | Pomegranate extract supplementation improves lung function parameters and IL-35 expression in participants with mild and moderate persistent allergic asthma: A randomized, double-blind, placebo-controlled trial |
| Pterostilbene | 📋 | ✍ | ⛔ | | 37069463 | Pterostilbene reduces the progression of atopic dermatitis via modulating inflammatory and oxidative stress biomarkers in mice |
| Puerarin | 📋 | ✍ | ⛔ | | 29524423 | The Suppressive Effect of Puerarin on Atopic Dermatitis-Like Skin Lesions Through Regulation of Inflammatory Mediators in Vitro and in Vivo |
| PUFA | 📋 | | | | 34658440 | The Importance of Maintaining a Low Omega-6/Omega-3 Ratio for Reducing the Risk of Autoimmune Diseases, Asthma, and Allergies |
| Raspberry | 📋 | ✍ | ⛔ | | 35179167 | Alleviation effects of Rubus coreanus Miquel root extract on skin symptoms and inflammation in chronic atopic dermatitis |
| Retinoic Acid | 📋 | | | | 38612663 | Retinoic Acid Treatment Mitigates PM2.5-Induced Type 2 Inflammation: Insights into Modulation of Innate Immune Responses |
| Salvianolic Acid | 📋 | | | | 34691223 | Salvianolic Acid A Suppresses DNCB-Induced Atopic Dermatitis-Like Symptoms in BALB/c Mice |
| Silibinin | 📋 | ✍ | | | 37115717 | Silibinin attenuated pseudo-allergic reactions and mast cell degranulation via PLCγ and PI3K/Akt signaling pathway |
| Tannic Acid | 📋 | ✍ | ⛔ | | 34126339 | Anti-asthmatic effects of tannic acid from Chinese natural gall nuts in a mouse model of allergic asthma |
| Turmeric | 📋 | ✍ | ⛔ | | 34932258 | Curcuma longa and curcumin affect respiratory and allergic disorders, experimental and clinical evidence: A comprehensive and updated review |
| Urolithins | 📋 | | | | 36961550 | Network pharmacology and molecular docking to explore the potential mechanism of urolithin A in combined allergic rhinitis and asthma syndrome |
| Vitamin K2 | 📋 | ✍ | ⛔ | | 33390552 | Vitamin K2 Suppresses Proliferation and Inflammatory Cytokine Production in Mitogen-Activated Lymphocytes of Atopic Dermatitis Patients through the Inhibition of Mitogen-Activated Protein Kinases |
| Vitexin | 📋 | | | | 35026520 | Vitexin restores lung homeostasis by targeting vicious loop between inflammatory aggravation and autophagy mediated via multiple redox cascade and myeloid cells alteration in experimental allergic asthma |
| Yogurt | 📋 | | ⛔ | | 37195509 | Impact of Habitual Yogurt Intake in Mother-Child Dyads on Incidence of Childhood Otitis Media: The Japan Environment and Children's Study (JECS) |
| 5-HTP | 📋 | ✍ | ⛔ | | 22842218 | Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan |
| Activated Charcoal | 📋 | ✍ | ⛔ | | 36582570 | The Utilization of Activated Charcoal in the Management of Anaphylaxis: A Case Series |
| Almond Oil | 📋 | | ⛔ | | 35751565 | Almond oil restores blood parameters, liver function, blood and liver antioxidants and DNA, and liver histology more efficiently than olive oil in favism |
| Aloin | 📋 | | | | 37781715 | Exploration of the mechanism of aloin ameliorates of combined allergic rhinitis and asthma syndrome based on network pharmacology and experimental validation |
| Amygdalin | 📋 | ✍ | ⛔ | | 38085145 | Amygdalin Improves Allergic Asthma via the Thymic Stromal Lymphopoietin-dendritic Cell-OX40 Ligand Axis in a Mouse Model |
| Andrographolide | 📋 | | | | 26929603 | Andrographolide suppresses thymic stromal lymphopoietin in phorbol myristate acetate/calcium ionophore A23187-activated mast cells and 2,4-dinitrofluorobenzene-induced atopic dermatitis-like mice model |
| Anthocyanins | 📋 | ✍ | ⛔ | | 32842205 | [To explore the therapeutic effect of myrtle oil, anthocyanin and hyaluronic acid in combination with topical application on allergic rhinitis in rats exposed to PM2.5] |
| Antioxidants | 📋 | | ⛔ | | 35502578 | Efficacy and safety profile of antioxidants in the treatment of atopic dermatitis: A systematic review and meta-analysis of randomized controlled trials |
| Arjuna | 📋 | ✍ | ⛔ | | 22392241 | Antimicrobial activity of Terminalia arjuna Wight & Arn.: an ethnomedicinal plant against pathogens causing ear infection |
| Ashwagandha | 📋 | ✍ | ⛔ | | 37405114 | Modulation of Immunological, Biochemical, and Histopathological Changes of Airway Remodeling by Withania somnifera in an Experimental Model of Allergic Asthma in Rats |
| Asiaticoside | 📋 | | | | 28891650 | Asiaticoside Mitigates the Allergic Inflammation by Abrogating the Degranulation of Mast Cells |
| Aspirin | 📋 | | ⛔ | | 37691954 | Potential causal association between aspirin use and the reduced risk of hayfever or allergic rhinitis: a Mendelian randomization study |
| Basil Essential Oil | 📋 | ✍ | ⛔ | | 15871121 | Effective treatment of experimental acute otitis media by application of volatile fluids into the ear canal |
| Bee Venom | 📋 | ✍ | ⛔ | | 31786805 | Anti-inflammatory effect of bee venom in phthalic anhydride-induced atopic dermatitis animal model |
| Beta-Glucan | 📋 | ✍ | ⛔ | | 38603862 | β-glucan mitigates ovalbumin-induced airway inflammation by preventing oxidative stress and CD8+ T cell infiltration |
| Bitter Melon | 📋 | ✍ | ⛔ | | 35257554 | Momordica charantia L. improves airway hyperresponsiveness and suppresses inflammation in a murine model of allergic asthma |
| Black Tea | 📋 | ✍ | ⛔ | | 34493326 | The extract of black cumin, licorice, anise, and black tea alleviates OVA-induced allergic rhinitis in mouse via balancing activity of helper T cells in lung |
| Blueberry | 📋 | ✍ | ⛔ | | 31295634 | Peanut protein-polyphenol aggregate complexation suppresses allergic sensitization to peanut by reducing peanut-specific IgE in C3H/HeJ mice |
| Calcium | 📋 | ✍ | ⛔ | | 16406247 | Dietary intake of seaweed and minerals and prevalence of allergic rhinitis in Japanese pregnant females: baseline data from the Osaka Maternal and Child Health Study |
| Camellia | 📋 | | ⛔ | | 37765323 | Camellia sinensis (L.) Kuntze Extract Attenuates Ovalbumin-Induced Allergic Asthma by Regulating Airway Inflammation and Mucus Hypersecretion |
| CAPE | 📋 | | | | 36183260 | Caffeic acid phenethyl ester inhibits pseudo-allergic reactions via inhibition of MRGPRX2/MrgprB2-dependent mast cell degranulation |
| Cardamonin | 📋 | | | | 34690788 | Allergic Inflammation Caused by Dimerized Translationally Controlled Tumor Protein is Attenuated by Cardamonin |
| Carnosic Acid | 📋 | | | | 36608933 | Carnosic acid inhibits secretion of allergic inflammatory mediators in IgE-activated mast cells via direct regulation of Syk activation |
| Carnosol | 📋 | | | | 32632049 | Suppressive Effect of Carnosol on Ovalbumin-Induced Allergic Asthma |
| Carvacrol | 📋 | ✍ | ⛔ | | 35555834 | Experimental and clinical evidence on the effect of carvacrol on respiratory, allergic, and immunologic disorders: A comprehensive review |
| Cat's Claw | 📋 | ✍ | ⛔ | | 29432856 | Aqueous extracts from Uncaria tomentosa (Willd. ex Schult.) DC. reduce bronchial hyperresponsiveness and inflammation in a murine model of asthma |
| Catechins | 📋 | | | | 35743851 | Ameliorative Effect of a Neoteric Regimen of Catechin plus Cetirizine on Ovalbumin-Induced Allergic Rhinitis in Rats |
| Celery | 📋 | | ⛔ | | 32202321 | Anti-atopic Dermatitis Effects of Hydrolyzed Celery Extract in Mice |
| Chamomile Essential Oil | 📋 | ✍ | ⛔ | | 31782320 | Evaluation of chamomile oil and nanoemulgels as a promising treatment option for atopic dermatitis induced in rats |
| Chondroitin | 📋 | ✍ | ⛔ | | 30521103 | Chondroitin sulfate inhibits secretion of TNF and CXCL8 from human mast cells stimulated by IL-33 |
| Chrysanthemum | 📋 | ✍ | ⛔ | | 22454686 | Topical Application of Chrysanthemum indicum L. Attenuates the Development of Atopic Dermatitis-Like Skin Lesions by Suppressing Serum IgE Levels, IFN-γ, and IL-4 in Nc/Nga Mice |
| Clove Essential Oil | 📋 | | ⛔ | | 36756486 | IN VITRO AND IN SILICO ANTIBACTERIAL ACTIVITIES OF SYZGIUM AROMATICUM ESSENTIAL OIL AGAINST BACTERIA ASSOCIATED WITH OTITIS MEDIA IN CHILDREN |
| Cocoa | 📋 | ✍ | ⛔ | | 30813439 | Relationship between Cocoa Intake and Healthy Status: A Pilot Study in University Students |
| Cornus | 📋 | | | | 33138027 | Cornus officinalis Ethanolic Extract with Potential Anti-Allergic, Anti-Inflammatory, and Antioxidant Activities |
| Coumaric acid | 📋 | | | | 33437169 | p-coumaric acid, an active ingredient of Panax ginseng, ameliolates atopic dermatitis-like skin lesions through inhibition of thymic stromal lymphopoietin in mice |
| Crocetin | 📋 | | | | 38286072 | Crocetin inhibits mast cell-dependent immediate-type allergic reactions through Ca2+/PLC/IP3 and TNF pathway |
| Cryptotanshinone | 📋 | | | | 29845271 | Cryptotanshinone inhibits IgE‑mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine‑protein kinase phosphorylation in mast cells |
| Dihydroquercetin | 📋 | | | | 30925321 | Inhibitory effect of taxifolin on mast cell activation and mast cell-mediated allergic inflammatory response |
| DIM | 📋 | ✍ | ⛔ | | 33309306 | 3,3'-Diindolylmethane alleviates acute atopic dermatitis by regulating T cell differentiation in a mouse model |
| Diosgenin | 📋 | | | | 33922675 | Anti-Allergic Diarrhea Effect of Diosgenin Occurs via Improving Gut Dysbiosis in a Murine Model of Food Allergy |
| Egg | 📋 | | ⛔ | | 34648974 | Inverse associations between food diversity in the 2 nd year of life and allergic diseases |
| Escin | 📋 | ✍ | ⛔ | | 23257653 | Escin inhibits type I allergic dermatitis in a novel porcine model |
| Essential Oils | 📋 | | ⛔ | | 38625386 | The use of essential oils in atopic dermatitis: a review |
| Fenugreek | 📋 | ✍ | ⛔ | | 27939889 | Trigonella Foenum-Graecum Alleviates Airway Inflammation of Allergic Asthma in Ovalbumin-Induced Mouse Model |
| Fiber | 📋 | ✍ | ⛔ | | 35990418 | Dietary fibre in relation to asthma, allergic rhinitis and sensitization from childhood up to adulthood |
| Fish | 📋 | | ⛔ | | 17634174 | Fish and fat intake and prevalence of allergic rhinitis in Japanese females: the Osaka Maternal and Child Health Study |
| Fish Collagen | 📋 | ✍ | ⛔ | | 37689763 | Anti-atopic dermatitis effect of fish collagen on house dust mite-induced mice and HaCaT keratinocytes |
| Flavonoids | 📋 | | ⛔ | | 35465348 | Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials |
| Fo-Ti Root | 📋 | ✍ | ⛔ | | 26916919 | Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma |
| Frankincense | 📋 | ✍ | ⛔ | | 37109265 | A Supplement with Ribes Nigrum, Boswellia Serrata, Bromelain and Vitamin D to Stop Local Inflammation in Chronic Sinusitis: A Case-Control Study |
| GABA | 📋 | ✍ | ⛔ | | 34868705 | Synergistic effect of Korean red ginseng extract and GABA mixture on the IgE production in mice via Th1/Th2 cell balance |
| Galangal | 📋 | ✍ | ⛔ | | 34656059 | Alpinia officinarum water extract inhibits the atopic dermatitis-like responses in NC/Nga mice by regulation of inflammatory chemokine production |
| Garlic | 📋 | ✍ | ⛔ | | 12728112 | Naturopathic Treatment for Ear Pain in Children |
| Geniposide | 📋 | | | | 34847477 | Gardenia jasminoides extract ameliorates DfE-induced atopic dermatitis in mice through restoration of barrier function and T-helper 2-mediated immune response |
| Genistein | 📋 | ✍ | ⛔ | | 32798538 | In utero exposure to genistein decreased intranasal house dust mite-induced respiratory allergy in middle-aged male B6C3F1 offspring |
| Geranium Essential Oil | 📋 | | ⛔ | | 27034695 | Effect of Inhalation of Aromatherapy Oil on Patients with Perennial Allergic Rhinitis: A Randomized Controlled Trial |
| Ginkgetin | 📋 | | | | 16651744 | Effects of anti-inflammatory biflavonoid, ginkgetin, on chronic skin inflammation |
| Ginkgo Biloba | 📋 | ✍ | ⛔ | | 19396774 | Clinical efficacy of a Ginkgo biloba extract in the topical treatment of allergic conjunctivitis |
| Ginkgolides | 📋 | | | | 22849842 | In vitro suppression of lymphocyte activation in patients with seasonal allergic rhinitis and pollen-related asthma by cetirizine or azelastine in combination with ginkgolide B or astaxanthin |
| Glycyrrhetinic Acid | 📋 | | | | 35210449 | 18β-Glycyrrhetinic acid suppresses allergic airway inflammation through NF-κB and Nrf2/HO-1 signaling pathways in asthma mice |
| Goji Berry | 📋 | ✍ | ⛔ | | 37780223 | Protective effect of Lycium barbarum leaf extracts on atopic dermatitis: in vitro and in vivo studies |
| Grape | 📋 | | ⛔ | | 36741360 | Protective effects of dietary grape against atopic dermatitis-like skin lesions in NC/NgaTndCrlj mice |
| Grape Seed extract | 📋 | ✍ | ⛔ | | 22836658 | Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma |
| Grapefruit | 📋 | | ⛔ | | 33752061 | Protective effects of total flavonoids from Qu Zhi Qiao (fruit of Citrus paradisi cv. Changshanhuyou) on OVA-induced allergic airway inflammation and remodeling through MAPKs and Smad2/3 signaling pathway |
| Green Tea | 📋 | ✍ | ⛔ | | 28190352 | Polyphenol Interactions Mitigate the Immunogenicity and Allergenicity of Gliadins |
| Haritaki | 📋 | ✍ | ⛔ | | 35830757 | Terminalia chebula Retz. extract ameliorates the symptoms of atopic dermatitis by regulating anti-inflammatory factors in vivo and suppressing STAT1/3 and NF-ĸB signaling in vitro |
| Honokiol | 📋 | | | | 35074454 | Honokiol suppresses 2,6-dinitrochlorobenzene-induced atopic dermatitis in mice |
| Hydroxytyrosol | 📋 | | | | 31645146 | Chemical composition, antioxidant activities, in an allergic asthma model, of Olea europaea L. leaf extracts from Collo (Skikda, Algeria) |
| Icariin | 📋 | ✍ | | | 37602424 | Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis |
| Indian Mulberry | 📋 | ✍ | ⛔ | | 36639978 | Morinda officinalis extract exhibits protective effects against atopic dermatitis by regulating the MALAT1/miR-590-5p/CCR7 axis |
| Inulin | 📋 | ✍ | ⛔ | | 38661353 | Inulin has a beneficial effect by modulating the intestinal microbiome in a BALB/c mouse model |
| Iron | 📋 | ✍ | ⛔ | | 35769558 | Iron-Deficiency in Atopic Diseases: Innate Immune Priming by Allergens and Siderophores |
| Isoliquiritigenin | 📋 | | | | 29026975 | Effect of isoliquiritigenin for the treatment of atopic dermatitis-like skin lesions in mice |
| Isorhamnetin | 📋 | | | | 37842252 | Effect of Polyphenols in Sea Buckthorn Berry on Chemical Mediator Release from Mast Cells |
| Jujube | 📋 | | ⛔ | | 38094286 | The Added-on of Ziziphus jujube Syrup in the Treatment of Chronic Spontaneous Urticaria Resistant to Standard-Dose of Secondary-generation H1 Antihistamine: A Double-Blind Randomized Clinical Trial |
| Kale | 📋 | | | | 35739968 | Skin Care Product Rich in Antioxidants and Anti-Inflammatory Natural Compounds Reduces Itching and Inflammation in the Skin of Atopic Dermatitis Patients |
| Kimchi | 📋 | | ⛔ | | 34737993 | Effect of Lactic Acid Strains Isolated from Kimchi on Atopic Dermatitis and Immunomodulation in NC/Nga Mice |
| Kudzu Root | 📋 | ✍ | ⛔ | | 35658632 | Isoorientin ameliorates OVA-induced asthma in a murine model of asthma |
| L-Histidine | 📋 | ✍ | ⛔ | | 33000160 | l-Histidine Supplementation in Adults and Young Children with Atopic Dermatitis (Eczema) |
| L-Proline | 📋 | ✍ | ⛔ | | 36532514 | Intestinal proline is a potential anti-allergy factor for allergy diagnosis and therapy |
| L-Tryptophan | 📋 | ✍ | ⛔ | | 38318507 | Tryptophan, an important link in regulating the complex network of skin immunology response in atopic dermatitis |
| Lavender Essential Oil | 📋 | ✍ | ⛔ | | 38181031 | Aromatic oil from lavender as an atopic dermatitis suppressant |
| Lemongrass | 📋 | ✍ | ⛔ | | 26048391 | The anti-allergic activity of Cymbopogon citratus is mediated via inhibition of nuclear factor kappa B (Nf-Κb) activation |
| Linoleic Acid | 📋 | ✍ | ⛔ | | 33865303 | A cream containing linoleic acid, 5% dexpanthenol and ceramide in the treatment of atopic dermatitis |
| Lipoic Acid | 📋 | ✍ | ⛔ | | 32719431 | Anti-allergic rhinitis activity of α-lipoic acid via balancing Th17/Treg expression and enhancing Nrf2/HO-1 pathway signaling |
| Liquiritin | 📋 | | | | 36816265 | Liquiritin inhibits MRGPRX2-mediated pseudo-allergy through the PI3K/AKT and PLCγ signaling pathways |
| Loquat | 📋 | ✍ | ⛔ | | 31310829 | Eriobotrya japonica leaf extract attenuates airway inflammation in ovalbumin-induced mice model of asthma |
| Lotus | 📋 | | ⛔ | | 36832810 | Oral Administration of Lotus-Seed Resistant Starch Protects against Food Allergy |
| Lupeol | 📋 | | | | 37098554 | Lupeol alleviates atopic dermatitis-like skin inflammation in 2,4-dinitrochlorobenzene/Dermatophagoides farinae extract-induced mice |
| Magnolia | 📋 | ✍ | ⛔ | | 37955529 | Effects of Magnoliae Flos on Atopic Dermatitis-Like Inflammation Evaluated via Extracellular Signal-regulated Kinase or Signal Transducers and Activators of Transcription 1/3 Signalling Pathways |
| Malva Sylvestris | 📋 | | ⛔ | | 33100212 | Efficacy of Short Term Topical Malva Sylvestris L. Cream in Pediatric Patients with Atopic Dermatitis: A Randomized Double-Blind Placebo-Controlled Clinical Trial |
| Marigold | 📋 | ✍ | ⛔ | | 34425472 | Effects of topical application of a tri-herb formula on inflammatory dry-skin condition in mice with oxazolone-induced atopic dermatitis |
| Mastic | 📋 | ✍ | ⛔ | | 34332283 | Topical treatment with mastic (resin from Pistacia lentiscus) elicits anti-inflammatory and anti-pruritic responses by modulating keratinocyte activation in a mouse model of allergic dermatitis |
| Motherwort | 📋 | ✍ | ⛔ | | 34421593 | Trigonelline, An Alkaloid From Leonurus japonicus Houtt., Suppresses Mast Cell Activation and OVA-Induced Allergic Asthma |
| MSM | 📋 | ✍ | ⛔ | | 30497995 | Evaluating the Impacts of Methylsulfonylmethane on Allergic Rhinitis After a Standard Allergen Challenge: Randomized Double-Blind Exploratory Study |
| Mulberry | 📋 | | ⛔ | | 36610150 | Morus alba fruits attenuates atopic dermatitis symptoms and pathology in vivo and in vitro via the regulation of barrier function, immune response and pruritus |
| Myrtle | 📋 | ✍ | ⛔ | | 32641957 | Anti-Inflammatory and Anti-Oxidative Effects of Myrtenol in the Rats with Allergic Asthma |
| Myrtle Essential Oil | 📋 | ✍ | ⛔ | | 32842205 | [To explore the therapeutic effect of myrtle oil, anthocyanin and hyaluronic acid in combination with topical application on allergic rhinitis in rats exposed to PM2.5] |
| Naringin | 📋 | ✍ | ⛔ | | 32698069 | Cellulose microsponges based gel of naringenin for atopic dermatitis: Design, optimization, in vitro and in vivo investigation |
| Nattokinase | 📋 | ✍ | ⛔ | | 28389065 | Nattokinase, Profibrinolytic Enzyme, Effectively Shrinks the Nasal Polyp Tissue and Decreases Viscosity of Mucus |
| Oak Bark | 📋 | ✍ | ⛔ | | 27725242 | Constituents from oak bark (Quercus robur L.) inhibit degranulation and allergic mediator release from basophils and mast cells in vitro |
| Oleanolic Acid | 📋 | | | | 37021507 | Oleanolic Acid Acetate Inhibits Mast Cell Activation in Ovalbumin-Induced Allergic Airway Inflammation |
| Osmanthus | 📋 | ✍ | ⛔ | | 24386002 | The Ethanol Extract of Osmanthus fragrans Flowers Reduces Oxidative Stress and Allergic Airway Inflammation in an Animal Model |
| Paeonol | 📋 | | | | 37224634 | Paeonol attenuates Substance P-induced urticaria by inhibiting Src kinase phosphorylation in mast cells |
| Papaya | 📋 | ✍ | ⛔ | | 28732802 | Carica papaya ameliorates allergic asthma via down regulation of IL-4, IL-5, eotaxin, TNF-α, NF-ĸB, and iNOS levels |
| Patchouli | 📋 | ✍ | ⛔ | | 26531835 | Anti-allergic and anti-inflammatory effects of aqueous extract of Pogostemon cablin |
| Pau d'Arco | 📋 | ✍ | ⛔ | | 29736153 | Tabetri™ ( Tabebuia avellanedae Ethanol Extract) Ameliorates Atopic Dermatitis Symptoms in Mice |
| PEA | 📋 | ✍ | ⛔ | | 38408443 | Efficacy of topical palmitoylethanolamide (Levagen+) for the management of eczema symptoms: A double blind, comparator controlled, randomized clinical trial |
| Peach | 📋 | | ⛔ | | 20633593 | Anti-allergic inflammatory activity of the fruit of Prunus persica: role of calcium and NF-kappaB |
| Peppermint | 📋 | ✍ | ⛔ | | 11201253 | Effects of peppermint (Mentha piperita L.) extracts on experimental allergic rhinitis in rats |
| Piperine | 📋 | ✍ | ⛔ | | 32392825 | Piperine Ameliorates Trimellitic Anhydride-Induced Atopic Dermatitis-Like Symptoms by Suppressing Th2-Mediated Immune Responses via Inhibition of STAT6 Phosphorylation |
| Polydatin | 📋 | ✍ | | | 36906289 | Polydatin inhibits mitochondrial damage and mitochondrial ROS by promoting PINK1-Parkin-mediated mitophagy in allergic rhinitis |
| Polypodium Leucotomos | 📋 | ✍ | ⛔ | | 22560125 | Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial |
| Pomegranate Seed extract | 📋 | | ⛔ | | 36762119 | Does pomegranate extract supplementation improve the clinical symptoms of patients with allergic asthma? A double-blind, randomized, placebo-controlled trial |
| Poria Mushrooms | 📋 | ✍ | | | 33919400 | Poria cocos Modulates Th1/Th2 Response and Attenuates Airway Inflammation in an Ovalbumin-Sensitized Mouse Allergic Asthma Model |
| PQQ | 📋 | ✍ | ⛔ | | 36345503 | Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway |
| Procyanidins | 📋 | | ⛔ | | 18594151 | Procyanidin C1 from apple extracts inhibits Fc epsilon RI-mediated mast cell activation |
| Punicalagin | 📋 | ✍ | ⛔ | | 36651367 | Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways |
| Quercitrin | 📋 | | | | 32695208 | Quercitrin, the Main Compound in Wikstroemia indica, Mitigates Skin Lesions in a Mouse Model of 2,4-Dinitrochlorobenzene-Induced Contact Hypersensitivity |
| Radish | 📋 | | ⛔ | | 38543055 | Anti-Atopic Effect of Scutellaria baicalensis and Raphanus sativus on Atopic Dermatitis-like Lesions in Mice by Experimental Verification and Compound-Target Prediction |
| Red Sage | 📋 | ✍ | ⛔ | | 30599896 | Protective effects and active ingredients of Salvia miltiorrhiza Bunge extracts on airway responsiveness, inflammation and remodeling in mice with ovalbumin-induced allergic asthma |
| Rehmannia | 📋 | ✍ | ⛔ | | 35168697 | Anti-atopic dermatitis effects of Parasenecio auriculatus via simultaneous inhibition of multiple inflammatory pathways |
| Saffron | 📋 | ✍ | ⛔ | | 32628613 | Neural Network-Based Clinical Prediction System for Identifying the Clinical Effects of Saffron (Crocus Sativus L) Supplement Therapy on Allergic Asthma: Model Evaluation Study |
| Salidroside | 📋 | | | | 32070919 | Salidroside suppresses group 2 innate lymphoid cell-mediated allergic airway inflammation by targeting IL-33/ST2 axis |
| Schisandrins | 📋 | | | | 35085518 | Schisandrin B promotes Foxp3 + regulatory T cell expansion by activating heme oxygenase-1 in dendritic cells and exhibits immunomodulatory effects in Th2-mediated allergic asthma |
| Scutellarein | 📋 | | | | 35771623 | Scutellarein Attenuates Atopic Dermatitis by Selectively Inhibiting Transient Receptor Potential Vanilloid 3 |
| Shiitake Mushrooms | 📋 | ✍ | ⛔ | | 27483228 | Chemical Composition and Inhibitory Effect of Lentinula edodes Ethanolic Extract on Experimentally Induced Atopic Dermatitis in Vitro and in Vivo |
| Shogaol | 📋 | | | | 34934427 | Ginger-derived compounds exert in vivo and in vitro anti-asthmatic effects by inhibiting the T-helper 2 cell-mediated allergic response |
| St. Johns Wort | 📋 | ✍ | ⛔ | | 12728112 | Naturopathic Treatment for Ear Pain in Children |
| St. Johns Wort Oil | 📋 | | ⛔ | | 12807340 | Topical Treatment of Atopic Dermatitis With St. John's Wort Cream--A Randomized, Placebo Controlled, Double Blind Half-Side Comparison |
| Star Anise | 📋 | ✍ | ⛔ | | 29062168 | Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3 + Regulatory T Cells and Inhibition of Th2 Cytokines in Mice |
| Stigmasterol | 📋 | | | | 36788676 | Stigmasterol alleviates allergic airway inflammation and airway hyperresponsiveness in asthma mice through inhibiting substance-P receptor |
| Stinging Nettle | 📋 | ✍ | ⛔ | | 38675586 | Evaluation of Urtica dioica Phytochemicals against Therapeutic Targets of Allergic Rhinitis Using Computational Studies |
| Sunflower | 📋 | | ⛔ | | 36108372 | Oral administration of Helianthus annuus leaf extract ameliorates atopic dermatitis by modulation of T cell activity in vivo |
| Sunflower Oil | 📋 | ✍ | ⛔ | | 38247218 | Ozonated Sunflower Oil (OSO) alleviates inflammatory responses in oxazolone-induced atopic dermatitis (AD)-like mice and LPS- treated RAW 264.7 cells |
| Tanshinone | 📋 | | | | 35167426 | Tanshinone IIA alleviates ovalbumin-induced allergic rhinitis symptoms by inhibiting Th2 cytokine production and mast cell histamine release in mice |
| Telmisartan | 📋 | | ⛔ | | 30826574 | Fisetin and telmisartan each alone or in low-dose combination alleviate OVA-induced food allergy in mice |
| Theaflavins | 📋 | ✍ | | | 36854953 | Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy |
| Thymol | 📋 | ✍ | ⛔ | | 30488351 | The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model |
| Thymoquinone | 📋 | | ⛔ | | 22768141 | Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, involving opioid receptors |
| Trans-Resveratrol | 📋 | | | | 18776917 | trans-Resveratrol, an Extract of Red Wine, Inhibits Human Eosinophil Activation and Degranulation |
| Tribulus Terrestris | 📋 | ✍ | ⛔ | | 29348776 | Effects of the Fruit Extract of Tribulus terrestris on Skin Inflammation in Mice with Oxazolone-Induced Atopic Dermatitis through Regulation of Calcium Channels, Orai-1 and TRPV3, and Mast Cell Activation |
| UDCA | 📋 | ✍ | ⛔ | | 38490296 | Ursodeoxycholic acid alleviates atopic dermatitis-associated inflammatory responses in HaCaT and RBL-2H3 cells and DNCB/DFE-treated mice |
| Ursolic Acid | 📋 | ✍ | ⛔ | | 36996741 | Ursolic acid ameliorates DNCB-induced atopic dermatitis-like symptoms in mice by regulating TLR4/NF-κB and Nrf2/HO-1 signaling pathways |
| Vitamin B6 | 📋 | ✍ | ⛔ | | 37217797 | Vitamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation |
| Walnut | 📋 | | ⛔ | | 35401757 | Amelioration of Ovalbumin-Induced Allergic Asthma by Juglans regia via Downregulation of Inflammatory Cytokines and Upregulation of Aquaporin-1 and Aquaporin-5 in Mice |
| White Fungus | 📋 | | | | 36091780 | Tremella fuciformis polysaccharides alleviate induced atopic dermatitis in mice by regulating immune response and gut microbiota |
| Witch Hazel | 📋 | ✍ | ⛔ | | 36012541 | Unveiling the Ability of Witch Hazel ( Hamamelis virginiana L.) Bark Extract to Impair Keratinocyte Inflammatory Cascade Typical of Atopic Eczema |
| Xylitol | 📋 | ✍ | ⛔ | | 38071837 | Xylitol nasal spray for prevention of recurrent acute otitis media in children: A prospective two-center cohort study |
| Zeaxanthin | 📋 | ✍ | ⛔ | | 36086967 | Zeaxanthin attenuates OVA-induced allergic asthma in mice by regulating the p38 MAPK/β-catenin signaling pathway |
